Film Peeling

Coating peels off tablet during coating process.

Tablet Core Tablet core ingredients do not promote good coating adhesion. Learn more.
  • Increase levels of hydrophilic ingredients such as microcrystalline cellulose, starch, copovidone or hydroxypropyl cellulose.
  • Optimize levels of lubricants such as magnesium stearate to minimize negative impact on coating adhesion, or replace magnesium stearate with other lubricants such as stearic acid or sodium stearyl fumarate.
Tablet core porosity is not sufficient to promote good adhesion. Learn more.
  • Increase tablet core porosity by reducing compaction forces. Note: Reduction should not be so much that tablet core robustness is compromised.
Tablet is not robust enough to withstand abrasion in coating pan.
  • Consider reformulating core (e.g., adding a more plastic binder such as hydroxypropyl cellulose) to increase robustness and minimize capping problems. Learn more.
  • Increase compaction forces to improve tablet robustness.
Coating Formulation Formulation has insufficient film strength to provide increased resistance to edge damage.
  • Consult with Ashland to select an Aquarius™ film coating system with increased mechanical strength and/or increased film flexibility.
  • Consult with Ashland to select an Aquarius film coating system with increased adhesion characteristics. Learn more.
Coating Process Coating is rubbing off due to excessive attritional effects.
  • Reduce pan speed.
Coating robustness is being affected by excessive heat in the coating process.
  • Reduce process air temperature and/or increase spray rate.