Scuffing of Film-coated Tablets

Scuffing involves the generation of gray-to-black marks on the surface of white (or lightly colored) film-coated tablets, thought to be an abrasion...
Read More
Excessive Roughness (Orange Peel)

The surface of the applied film coating is extremely rough, often taking on the appearance of the skin of an...
Read More
Excessive Tablet-to-Tablet Color Variability

Visible differences in color, tablet-to-tablet, are readily...
Read More
Tablet Twinning

Tablets become stuck together, usually after becoming aligned along flat...
Read More
Tablet Surface Erosion

Tablet surfaces erode as tablets tumble during the coating process. Problem is compounded by the presence of a...
Read More
Tablet Edge Chipping/Erosion

The edges of the tablets are worn away, or chipped, as the coating is being...
Read More
Tablet Discoloration

Discoloration is seen either through or on the coating, caused by interactions of ingredients in the core or by heat from the process causing...
Read More
Picking and Sticking

Tablets momentarily stick together, often just after they pass through the spray zone, and then break apart leaving defects in the surface of the...
Read More
Logo Bridging

As more coating is applied to tablet surfaces, the stresses that develop within the coating as it dries overcome the forces of attachment of the...
Read More
In-filling of Logos/Break Lines

Coating droplets are over-dried before contacting tablet surface, increasing tablet surface roughness and filling in the logo, thus reducing...
Read More
Tablet Breakage

Tablets break apart. This can happen during pan loading, during the coating process, or during unloading of the coating...
Read More
Film Cracking

Coated tablets exhibit micro- or macroscopic cracks across the...
Read More
Film Peeling

Coating peels off tablet during coating...
Read More
Tablet Dissolution

Dissolution problems with film-coated tablets occur when there is a statistically significant change in dissolution behavior after film coating...
Read More