Scuffing of Film-coated Tablets
Scuffing involves the generation of gray-to-black marks on the surface of white (or lightly colored) film-coated tablets, thought to be an abrasion...
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Excessive Roughness (Orange Peel)
The surface of the applied film coating is extremely rough, often taking on the appearance of the skin of an...
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Excessive Tablet-to-Tablet Color Variability
Visible differences in color, tablet-to-tablet, are readily...
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Tablet Twinning
Tablets become stuck together, usually after becoming aligned along flat...
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Tablet Surface Erosion
Tablet surfaces erode as tablets tumble during the coating process. Problem is compounded by the presence of a...
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Tablet Edge Chipping/Erosion
The edges of the tablets are worn away, or chipped, as the coating is being...
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Tablet Discoloration
Discoloration is seen either through or on the coating, caused by interactions of ingredients in the core or by heat from the process causing...
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Picking and Sticking
Tablets momentarily stick together, often just after they pass through the spray zone, and then break apart leaving defects in the surface of the...
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Logo Bridging
As more coating is applied to tablet surfaces, the stresses that develop within the coating as it dries overcome the forces of attachment of the...
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In-filling of Logos/Break Lines
Coating droplets are over-dried before contacting tablet surface, increasing tablet surface roughness and filling in the logo, thus reducing...
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Tablet Breakage
Tablets break apart. This can happen during pan loading, during the coating process, or during unloading of the coating...
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Film Cracking
Coated tablets exhibit micro- or macroscopic cracks across the...
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Film Peeling
Coating peels off tablet during coating...
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Tablet Dissolution
Dissolution problems with film-coated tablets occur when there is a statistically significant change in dissolution behavior after film coating...
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